Anal cancers are rare malignant tumours of the rectum and of the anal canal. The degree of malignancy depends on its location, size, depth, expansion and histologic composition. The carcinoma of the rectum is attributed to skin tumours, but has a better chance of cure because they usually are recognized at an early stage. The carcinoma of the anal canal, however, is often diagnosed late.
Various factors play a role in the development of anal cancer. For example, rectum cancer arises from precancerous lesions which are sometimes misinterpreted as eczema, and develops over many years. The cancer development can be promoted by certain virus types with a weakened immune system. Anal warts can also grow into an anal cancer. Immunodeficiency (e.g., AIDS), passive anal intercourse, and smoking, are risk factors.
Signs of an anal carcinoma can be blood coming from the anus and nodular indurations of the rectum. Cramping pain, irregular stools and involuntary bowel movement suggest an advanced stage of anal cancer, as well as enlarged rough inguinal lymph nodes. Inspection of the outer and inner anal region with the finger leads to the diagnosis which is secured by a tissue sample. Also instrumental examination is required for tumours in the anal canal.
For smaller, i.e. rather superficially located tumours, especially of the rectum and the lower anal canal, surgical treatment is the first option. Surgical treatment is also a first option with greater depth extension into the anal canal. At greater depth extension and/or localization of tumours in the upper anal canal, a combination of radiotherapy and chemotherapy takes place. Unfortunately, anal cancers infiltrate very early in the muscles of the sphincter, so when surgery is used, saving this muscle is usually not possible.
Anal Carcinoma of the lower anal canal and the rectum occur in men about three to four times as often as women, while anal cancers of the upper anal canal more frequently occur in women. Anal canal cancers occur predominantly from the age of 60. These cancers in an earlier age occur in immune deficiency (AIDS, blood cancer, immunocompromised organ transplanted patients).
Recommended therapies for the treatment of rectum cancer:
Photodynamic Therapy (PDT)
We recommend our patients with rectum cancer in the Hyperthermia Center Hannover, the photodynamic therapy (PDT), in which specifically affected cells are destroyed with light. In the process, a light-activating substance (a so-called photosensitizer) is injected. This triggers a chemical reaction in combination with light of a specific wavelength in the affected cells, which leads to cell death. The surrounding healthy tissue is spared.
Whole body Hyperthermia
The healing effect of whole-body hyperthermia for patients with rectum cancer is that we can very quickly bring the body to high temperatures (up 40.5 ° Celsius). This fast and high heating activates not only the immune system, but many degenerate cells of the rectum carcinoma are destroyed by the fast flooding of heat. In addition to the damage or removal of the cancer cells, the whole-body hyperthermia stimulates the immune system enormously without impacting the rest of the body. It triggers an immune cascade that activates and multiplies the white blood cells.
Loco regional Hyperthermia
In Hyperthermia center regional hyperthermia is also advisable for rectum cancer: in this treatment the affected region is quickly heated to high temperatures (40 up to 44 ° C). This heat activates the immune system. Many cells of the rectum cancer will be harmed or destroyed. In our out-patient clinic at the Hyperthermia Center Hannover we offer the partial body hyperthermia depending on the diagnosis, in which only damaged or degenerated tissue is overheated, which guarantees very gentle treatment to our patients.
Based on our experience in the Hyperthermia Center Hannover, our patients with rectum cancer respond well to the ozone therapy. Ozone is a triatomic oxygen molecule. Its germicidal and disinfecting effect has been scientifically proven. In ozone treatment, the acute oxygen problem of the degenerated cells of the tumor is exploited. Blood is taken from the vein. This blood will be made incoagualble and then mixed with an ozone-oxygen mixture. The thus enriched blood is returned to the vein.
Infusions with high-dose vitamin C
At the Hyperthermia Center Hannover we treat patients with rectum cancer successfully with high-doses of vitamin C. The so-called Ascorbic acid is the best known vitamin, – and the most important antioxidant, i.e. it intercepts harmful free radicals in the body and makes them harmless – and in this way prevents degeneration in the cells. Vitamin C is also essential for the immune system and various restructuring processes in the body. When vitamin C is given in a high dose, the treatment of rectum cancer can be positively affected.